Hematopoietic Cell Transplantation for Tolerance Induction : Animal Models to Clinical TrialsSYKES, Megan.Transplantation. 2009, Vol 87, Num 3, pp 309-316, issn 0041-1337, 8 p.Article

Mechanisms of Transplantation Tolerance in Animals and HumansSYKES, Megan.Transplantation. 2009, Vol 87, Num 9S, issn 0041-1337, S67-S69, SUPConference Paper

Mixed chimerism and transplantation toleranceWEKERLE, Thomas; SYKES, Megan.Annual review of medicine. 2001, Vol 52, pp 353-370, issn 0066-4219Article

The role of antigen-presenting cells in triggering graft-versus-host disease and graft-versus-leukemiaCHAKRAVERTY, Ronjon; SYKES, Megan.Blood. 2007, Vol 110, Num 1, pp 9-17, issn 0006-4971, 9 p.Article

Treatment of severe autoimmune disease by stem-cell transplantationSYKES, Megan; NIKOLIC, Boris.Nature (London). 2005, Vol 435, Num 7042, pp 620-627, issn 0028-0836, 8 p.Article

Induction of toleranceWEKERLE, Thomas; SYKES, Megan.Surgery. 2004, Vol 135, Num 4, pp 359-364, issn 0039-6060, 6 p.Article

Tolerance and cancer: Mechanisms of tumor evasion and strategies for breaking toleranceMAPARA, Markus Y; SYKES, Megan.Journal of clinical oncology. 2004, Vol 22, Num 6, pp 1136-1151, issn 0732-183X, 16 p.Article

Anti-CD40L monoclonal antibodies can replace anti-CD4 monoclonal antibodies for the nonmyeloablative induction of mixed xenogeneic chimerismITO, Hiroshi; TAKEUCHI, Yasuo; SHAFFER, Juanita et al.Transplantation. 2006, Vol 82, Num 2, pp 251-257, issn 0041-1337, 7 p.Article

Position paper of the Ethics Committee of the International Xenotransplantation AssociationSYKES, Megan; D'APICE, Anthony; SANDRIN, Mauro et al.Transplantation. 2004, Vol 78, Num 8, pp 1101-1107, issn 0041-1337, 7 p.Article

Mixed hematopoietic chimerism for the simultaneous induction of T and B cell toleranceSYKES, Megan; SHIMIZU, Ichiro; KAWAHARA, Toshiyasu et al.Transplantation. 2005, Vol 79, Num 3, pp S28-S29, issn 0041-1337, SUPConference Paper

Local irradiation enhances congenic donor pluripotent hematopoietic stem cell engraftment similarly in irradiated and nonirradiated sitesITO, Hiroshi; TAKEUCHI, Yasuo; SHAFFER, Juanita et al.Blood. 2004, Vol 103, Num 5, pp 1949-1954, issn 0006-4971, 6 p.Article

Donor lymphocyte infusion-mediated graft-versus-leukemia effects in mixed chimeras established with a nonmyeloablative conditioning regimen: Extinction of graft-versus-leukemia effects after conversion to full donor chimerismMAPARA, Markus Y; KIM, Yong-Mi; MARX, Julie et al.Transplantation. 2003, Vol 76, Num 2, pp 297-305, issn 0041-1337, 9 p.Article

4.Non-myeloblative induction of mixed hematopoietic chimerism: Application to transplantation tolerance and hematologic malignancies in experimental and clinical studiesSYKES, Megan; SPITZER, Thomas R.Cancer treatment and research. 2002, Vol 110, pp 79-99, issn 0927-3042, 21 p.Article

Donor-derived interferon γ separates graft-versus-leukemia effects and graft-versus-host disease induced by donor CD8 T cellsYANG, Yong-Guang; QI, Jin; WANG, Min-Guang et al.Blood. 2002, Vol 99, Num 11, pp 4207-4215, issn 0006-4971Article

Mixed chimerism induces donor-specific T-cell tolerance across a highly disparate xenogeneic barrierABE, Masahiro; JIN QI; SYKES, Megan et al.Blood. 2002, Vol 99, Num 10, pp 3823-3829, issn 0006-4971Article

CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote toleranceKURTZ, Josef; RAVAL, Forum; VALLOT, Casey et al.Blood. 2009, Vol 113, Num 15, pp 3475-3484, issn 0006-4971, 10 p.Article

Mechanisms of early peripheral CD4 T-cell tolerance induction by anti-CD 154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion but not regulatory cellsKURTZ, Josef; SHAFFER, Juanita; LIE, Ariadne et al.Blood. 2004, Vol 103, Num 11, pp 4336-4343, issn 0006-4971, 8 p.Article

Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunityNIKOLIC, Boris; TAKEUCHI, Yasno; LEYKIN, Igor et al.Diabetes (New York, NY). 2004, Vol 53, Num 2, pp 376-383, issn 0012-1797, 8 p.Article

Despite efficient intrathymic negative selection of host-reactive T cells, autoimmune disease may develop in porcine thymus-grafted athymic mice: Evidence for failure of regulatory mechanisms suppressing autoimmunityYONG ZHAO; RODRIGUEZ-BARBOSA, Jose-Ignacio; SHIMIZU, Akira et al.Transplantation. 2003, Vol 75, Num 11, pp 1832-1840, issn 0041-1337, 9 p.Article

Long-term survival of xenogeneic heart grafts achieved by costimulatory blockade and transient mixed chimerismMURAKAMI, Masanori; ITO, Hiroshi; HARADA, Eijiro et al.Transplantation. 2006, Vol 82, Num 2, pp 275-281, issn 0041-1337, 7 p.Article

Short-term immunosuppression facilitates induction of mixed chimerism and tolerance after bone marrow transplantation without cytoreductive conditioningBLAHA, Peter; BIGENZAHN, Sinda; KOPORC, Zvonimir et al.Transplantation. 2005, Vol 80, Num 2, pp 237-243, issn 0041-1337, 7 p.Article

B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-αGAL-producing B-1 cellsSHIMIZU, Ichiro; KAWAHARA, Toshiyasu; HASPOT, Fabienne et al.Blood. 2007, Vol 109, Num 4, pp 1773-1781, issn 0006-4971, 9 p.Article

Cell therapy with preimmunized effector cells mismatched for minor histocompatible antigens in the treatment of a murine mammary carcinoma. CommentarySYKES, Megan; MORECKI, Shoshana; YACOVLEV, Elena et al.Journal of immunotherapy (1997). 2001, Vol 24, Num 2, pp 101-103, issn 1524-9557, 11 p.Article

International Human Xenotransplantation InventorySGROI, Antonino; BÜHLER, Leo H; MOREL, Philippe et al.Transplantation. 2010, Vol 90, Num 6, pp 597-603, issn 0041-1337, 7 p.Article

Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse modelTONOMURA, Noriko; HABIRO, Katsuyoshi; SHIMIZU, Akira et al.Blood. 2008, Vol 111, Num 8, pp 4293-4296, issn 0006-4971, 4 p.Article